5 Questions Oprah Should Ask Lance

His story has never changed. In front of cameras, microphones, fans, sponsors, cancer survivors—even under oath—Lance Armstrong hasn't just denied ever using performance enhancing drugs, he's done so in an indignant, even threatening way.

Today, sources tell ABC News, will be different. Today Armstrong is expected to rewrite his own, now infamous story, to Oprah Winfrey. So what should she ask? There are enough questions to fill a book, but here's our shot at five, for starters, all based on the belief that his first words will be an admission. Feel free to comment and add your own.

1) Witnesses have told the U.S. Anti Doping Agency that after recovering from cancer, you increased your use of performance enhancing drugs, but swore off one of them—Human Growth Hormone—specifically noting your cancer as a reason to avoid it. Do you believe your cancer may have been caused by performance enhancing drug use?

2) Some people seem able to forgive or rationalize the use of performance enhancing drugs, but what troubles them is the vicious cover-up. Why did you feel it necessary to go beyond denials, to attack and even threaten and file legal claims against those who accused you of drug use, even to the point of causing serious harm to people's lives and reputations?

3) In 1996, while recovering from cancer, your former close friend Frankie Andreu and his wife Betsy say they were in the hospital room when you told doctors you'd used several different performance enhancing drugs during your career. They testified under oath about this, but you always denied it and vilified them. This caused the Andreus great harm. Did it happen?

4) What do you tell your kids?

5) Up until today, everything you've said and done—even that picture on twitter of you and your yellow jerseys—has said to the world that you're not sorry, and that you're the real winner of seven Tours. Aren't you just coming forward now to help yourself, rather than to come clean or set the record straight?

Whatever the answers, a small army of lawyers and even criminal investigators will be listening closely. Will Armstrong's interview be the start of his redemption or the beginning of even bigger problems?

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